Article
Molecular approaches to amyotrophic lateral sclerosis.
Annual review of medicine - 1 Jan 1995
Smith R G, Appel S H
Abstract excerpt
New discoveries are expanding our knowledge of mechanisms involved in amyotrophic lateral sclerosis (ALS) pathogenesis. Some recent advances in our understanding of motoneuron death in familial ALS (fALS) and sporadic ALS (sALS) are reviewed, with emphasis on molecular similarities that may furth...
Topics
- Amyotrophic Lateral Sclerosis
- Autoimmune Diseases
- Free Radicals
- Glutamic Acid
- Humans
- Isoenzymes
- Motor Neurons
- Mutation
- Nerve Degeneration
- Phenotype
- Superoxide Dismutase
- Survival Rate