Article
Research advances in amyotrophic lateral sclerosis, 2009 to 2010.
Current neurology and neuroscience reports - 1 Feb 2011
Traub Rebecca, Mitsumoto Hiroshi, Rowland Lewis P
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of upper and lower motor neurons that causes progressive weakness and death. The breadth of research in ALS continues to grow with exciting new discoveries in disease pathogenesis and potential future therapeutics. There is a growing list of identified mutations in familial ALS, including those in genes encoding TDP-43 and FUS/TLS, which are...
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