Article
Protein phosphatase 2B of Saccharomyces cerevisiae is required for tolerance to manganese, in blocking the entry of ions into the cells.
European journal of biochemistry - 15 Sept 1995
Farcasanu I C, Hirata D, Tsuchiya E, Nishiyama F, Miyakawa T
Abstract excerpt
The role of protein phosphatase 2B (PP2B/calcineurin) of Saccharomyces cerevisiae in the tolerance to divalent cations was investigated. PP2B-deficient mutants were found to be sensitive to MnCl2, but not to ZnCl2, CuCl2, NiCl2 and CoCl2. By measuring both manganese uptake and its efflux, it was...
Topics
- Biological Transport
- Drug Resistance, Microbial
- Immunosuppressive Agents
- Magnesium
- Manganese
- Mutation
- Phosphoprotein Phosphatases
- Saccharomyces cerevisiae
- Tacrolimus
