Article
Population frequency of apolipoprotein E5 (Glu3-->Lys) and E7 (Glu244-->Lys, Glu245-->Lys) variants in western Japan.
Clinical genetics - 1 Aug 1995
Matsunaga A, Sasaki J, Moriyama K, Arakawa F, Takada Y, Nishi K, Hidaka K, Arakawa K
Abstract excerpt
Apolipoprotein (apo) E modulates the catabolism of chylomicrons and of very low density lipoprotein remnants. It has three major isoforms (apo E2, E3, E4) and some rare variants. To detect the variants of apo E, blood specimens from 1269 Japanese subjects were analyzed using isoelectric focusing...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Apolipoprotein E3
- Apolipoproteins E
- Base Sequence
- Female
- Genetic Variation
- Humans
- Japan
- Male
- Middle Aged
- Molecular Sequence Data
- Polymerase Chain Reaction
