Article
Frequency and role of apo E phenotype in familial hypercholesterolemia and non-familial hyperlipidemia in the Japanese.
Atherosclerosis - 1 Jun 1990
Kitahara M, Shinomiya M, Shirai K, Saito Y, Yoshida S
Abstract excerpt
The frequencies of the major apolipoprotein E(apo E) phenotypes in 65 normal, 426 hyperlipidemics, and 92 familial hypercholesterolemic Japanese subjects (FH) were studied, and features of hyperlipidemia compared between non-FH hyperlipidemia and FH. The frequencies of apo E phenotypes 3/3, 4/3, 3/2, 4/4 were almost the same in normal, non-FH hyperlipidemic, and FH subjects. The incidence of apo E7 was about 0.5%...
Topics
- Apolipoproteins E
- Humans
- Hyperlipidemias
- Hyperlipoproteinemia Type II
- Japan
- Lipids
- Lipoproteins
- Phenotype