Article
Atherosclerotic disease in marked hyperalphalipoproteinemia. Combined reduction of cholesteryl ester transfer protein and hepatic triglyceride lipase.
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1995
Hirano K, Yamashita S, Kuga Y, Sakai N, Nozaki S, Kihara S, Arai T, Yanagi K, Takami S, Menju M
Abstract excerpt
Hyperalphalipoproteinemia (HALP) has been regarded as a beneficial state accompanied by a longevity syndrome. However, we reported the cases of markedly hyperalphalipoproteinemic subjects with juvenile corneal opacification. The patients had reduced postheparin hepatic triglyceride lipase (HTGL) activities, and one of them has recently been identified to be homozygous for a missense mutation in exon 15 (D442: G)...
Topics
- Adult
- Aged
- Apolipoproteins
- Arteriosclerosis
- Biomarkers
- Carrier Proteins
- Cholesterol Ester Transfer Proteins
- Female
- Glycoproteins
- Humans
- Hyperlipoproteinemias