Molecular defects in thyroid carcinomas: role of the RET oncogene in thyroid neoplastic transformation.

Abstract excerpt

Tumors are believed to arise as a result of an accumulation of mutations in critical genes involved in the control of cell proliferation. Thyroid neoplasms represent a good model for studying the role of these mutations in epithelial cell multistep carcinogenesis because they comprise a broad spectrum of lesions with different degrees of malignancy. Recent reports have described the involvement of specific...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Transformation, Neoplastic
• Share to Drosophila Proteins