Article
Batched analysis of genotypes.
PCR methods and applications - 1 Jun 1995
LeDuc C, Miller P, Lichter J, Parry P
Abstract excerpt
Polymorphic microsatellite markers are widely used in molecular analyses. The range of allele sizes and the allele frequencies within a population are important characteristics of the marker. Their determination previously has involved genotyping a large number of individuals. We have developed a technique for defining these characteristics by coamplification of many samples in a DNA pool. Groups of 32 and 42 DNA...
Topics
- Alleles
- Base Sequence
- DNA
- DNA, Satellite
- Genotype
- Humans
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Regression Analysis
- Reproducibility of Results