Screening for PIT1 abnormality by PCR direct sequencing method.

doi:10.1089/thy.1995.5.207

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Article

Screening for PIT1 abnormality by PCR direct sequencing method.

Thyroid : official journal of the American Thyroid Association - 1 Jun 1995

Irie Y, Tatsumi K, Kusuda S, Kawawaki H, Boyages S C, Nose O, Ichiba Y, Katsumata N, Amino N

Abstract excerpt

PIT1 abnormality is defined as a genetic abnormality in the PIT1 gene, which encodes a pituitary specific transcription factor Pit-1/GHF-1.PIT1 abnormality has been reported in several patients displaying either complete or incomplete deficiency of thyrotropin (TSH), growth hormone (GH), and prolactin (PRL) in either familial or sporadic cases. To see if there are abnormalities in the PIT1 gene in patients with...

Topics

Base Sequence
Carrier Proteins
Female
Germ-Line Mutation
Growth Hormone
Humans
Male
Membrane Proteins
Molecular Sequence Data
Mutation
Phospholipid Transfer Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pituitary Hormones

Point Mutation

Polymerase Chain Reaction

Prolactin

Saccharomyces cerevisiae Proteins

Thyroid Hormones

Thyrotropin

Source

Open in PubMed

Identifiers

PMID: 7580269
DOI: 10.1089/thy.1995.5.207

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7580269-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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