Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome.

doi:10.1016/0959-8049(95)00025-e

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome.

European journal of cancer (Oxford, England : 1990) - 1 Jan 1995

Hedborg F, Bjelfman C, Sparén P, Sandstedt B, Påhlman S

Abstract excerpt

Neuroblastoma is an embryonal tumour of the sympathetic nervous system with marked heterogeneity in terms of histological maturity and clinical course. A previous study revealed that high tumour levels of the csrc protein, particularly its neuronal isoform (pp60csrcN), correlated with favourable outcome. To test whether this feature reflects a higher degree of neuronal maturation in these tumours, an extended...

Topics

Age Factors
Biomarkers, Tumor
Cell Differentiation
Child
Child, Preschool
Follow-Up Studies
Humans
Infant
Infant, Newborn
Neuroblastoma
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phosphopyruvate Hydratase

Prognosis

Proto-Oncogene Proteins pp60(c-src)

Survival Rate

Synaptophysin

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 7576941
DOI: 10.1016/0959-8049(95)00025-e

Genes

MYCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7576941-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Biochemical evidence for a mature phenotype in morphologically poorly differentiated neuroblastomas with a favourable outcome.PMID 7576941Read ↗

Neuroblastoma aggressiveness in relation to sympathetic neuronal differentiation stageSemantic proximity Read ↗

The expression profile of alternatively spliced neuronal c-src RNA distinguishes between human tumours of the sympatho-adrenal lineage.Semantic proximity Read ↗

[The immunological cellular phenotype and the prognosis in neuroblastoma in children].Semantic proximity Read ↗

Neuroblastoma: biological insights into a clinical enigma.Semantic proximity Read ↗

Neuroblastoma: an enigmatic diseaseSemantic proximity Read ↗

Neuroblastoma: the impact of biology and cooperation leading to personalized treatments.Semantic proximity Read ↗

High Myc pathway activity and low stage of neuronal differentiation associate with poor outcome in neuroblastomaSemantic proximity Read ↗

Large cell neuroblastoma: a distinct phenotype of neuroblastoma with aggressive clinical behavior.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.