Article
T cell awareness of paternal alloantigens during pregnancy.
Science (New York, N.Y.) - 27 Oct 1995
Tafuri A, Alferink J, Möller P, Hämmerling G J, Arnold B
Abstract excerpt
During pregnancy a semiallogeneic fetus survives despite the presence of maternal T cells specific for paternally inherited histocompatibility antigens. A mouse transgenic for a T cell receptor recognizing the major histocompatibility (MHC) antigen H-2Kb was used to follow the fate of T cells reactive to paternal alloantigens. In contrast to syngeneic and third-party allogeneic pregnancies, mice bearing a...
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