Article
T cell awareness of paternal alloantigens during pregnancy.
Science (New York, N.Y.) - 27 Oct 1995
Tafuri A, Alferink J, Möller P, Hämmerling G J, Arnold B
Abstract excerpt
During pregnancy a semiallogeneic fetus survives despite the presence of maternal T cells specific for paternally inherited histocompatibility antigens. A mouse transgenic for a T cell receptor recognizing the major histocompatibility (MHC) antigen H-2Kb was used to follow the fate of T cells rea...
Topics
- Animals
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Fathers
- Female
- Fetus
- Graft Rejection
- H-2 Antigens
- Immune Tolerance
- Male
- Mice
- Mice, Inbred C57BL
- Mice, SCID
- Mice, Transgenic
- Neoplasm Transplantation
- Phenotype
- Placenta
- Pregnancy