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PREGNANCY CAN INDUCE PRIMING OF CYTOTOXIC T LYMPHOCYTES SPECIFIC FOR PATERNAL HLA ANTIGENS THAT IS ASSOCIATED WITH ANTIBODY FORMATION

1 Sept 1996

Abstract excerpt

Some transplant centers consider paternal HLA antigens as unacceptable mismatches for mothers awaiting kidney transplantation. It is feared that a pregnancy may cause priming of the maternal immune response directed toward paternal HLA antigens. Should a woman receive an organ from a donor who shares those paternal HLA antigens, the risk of graft rejection might be increased. It is known that some women, as a...

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Share to Organ Transplantation Techniques and Outcomes
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PMID: 8830835
DOI: 10.1097/00007890-199609150-00023

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