Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 26 Sept 1995

Link C D

Abstract excerpt

Transgenic Caenorhabditis elegans nematodes have been engineered to express potentially amyloidic human proteins. These animals contain constructs in which the muscle-specific unc-54 promoter/enhancer of C. elegans drives the expression of the appropriate coding regions derived from human cDNA clones. Animals containing constructs expressing the 42-amino acid beta-amyloid peptide (derived from human amyloid...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Base Sequence
Share to DNA Primers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epitopes

Share to Genotype

Share to Immunohistochemistry

Share to Molecular Sequence Data

Share to Recombinant Fusion Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 7568134
DOI: 10.1073/pnas.92.20.9368
PMCID: PMC40986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans.PMID 7568134Read ↗

Human amyloid β peptide and tau co-expression impairs behavior and causes specific gene expression changes in Caenorhabditis elegansSemantic proximity Read ↗

In Vivo Aggregation of β‐Amyloid Peptide VariantsSemantic proximity Read ↗

Levels of Amyloid Beta (Aβ) Expression in the Caenorhabditis elegans Neurons Influence the Onset and Severity of Neuronally Mediated Phenotypes.Semantic proximity Read ↗

Synergistic toxicity between tau and amyloid drives neuronal dysfunction and neurodegeneration in transgenic C. elegansSemantic proximity Read ↗

Transgenic C. elegans as a model in Alzheimer's research.Semantic proximity Read ↗

A Caenorhabditis elegans model of tau hyperphosphorylation: Induction of developmental defects by transgenic overexpression of Alzheimer's disease-like modified tauSemantic proximity Read ↗

Increased lifespan in transgenic Caenorhabditis elegans overexpressing human alpha-synuclein.Semantic proximity Read ↗

Alzheimer's disease and tauopathy studies in flies and worms.Semantic proximity Read ↗

Identification of gene expression changes in transgenic C. elegans overexpressing human α-synucleinSemantic proximity Read ↗

Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegans for drug screening for Alzheimer’s diseaseSemantic proximity Read ↗

Caenorhabditis elegans Models to Investigate the Mechanisms Underlying Tau Toxicity in TauopathiesSemantic proximity Read ↗

Expression of A2V-mutated Aβ in Caenorhabditis elegans results in oligomer formation and toxicity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.