The pattern of adriamycin-induced mutations in V-E5 Chinese hamster cells with chromosomal instability.

doi:10.1016/0165-7992(95)90013-6

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Article

The pattern of adriamycin-induced mutations in V-E5 Chinese hamster cells with chromosomal instability.

Mutation research - 1 Sept 1995

Helbig R, Speit G

Abstract excerpt

The V-E5 cell line, a mutant V79 Chinese hamster cell line, was used to study the effect of chromosomal instability on the spectrum of gene mutations and chromosome aberrations induced by the anthracycline antibiotic adriamycin (AM). V-E5 cells showed hypersensitivity to the cytotoxic effects of...

Topics

Animals
Cell Line
Chromosome Aberrations
Chromosome Deletion
Cricetinae
Cricetulus
Doxorubicin
Hypoxanthine Phosphoribosyltransferase
Mutagenesis
Mutagenicity Tests
Mutagens
Mutation

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