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Article

P DNA element movement in somatic cells reduces lifespan in Drosophila melanogaster: evidence in support of the somatic mutation theory of aging.

Mutation research - 1 Oct 1995

Woodruff R C, Nikitin A G

Abstract excerpt

Evidence is presented in support of the hypothesis that P DNA element movement in somatic cells of Drosophila melanogaster induces genetic damage that significantly reduces lifespan. The lifespan of D. melanogaster males was significantly reduced by the somatic movement of a single P element in the presence of P[ry+ delta 2-3](99B) transposase. In addition, the P[ry+ SalI](89D) repressor of P[ry+ delta 2-3](99B)...

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Identifiers

PMID: 7565880
DOI: 10.1016/0921-8734(95)00009-u

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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