Article
P DNA element movement in somatic cells reduces lifespan in Drosophila melanogaster: evidence in support of the somatic mutation theory of aging.
Mutation research - 1 Oct 1995
Woodruff R C, Nikitin A G
Abstract excerpt
Evidence is presented in support of the hypothesis that P DNA element movement in somatic cells of Drosophila melanogaster induces genetic damage that significantly reduces lifespan. The lifespan of D. melanogaster males was significantly reduced by the somatic movement of a single P element in t...
Topics
- Aging
- Animals
- Chromosomes
- DNA Damage
- DNA Transposable Elements
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Longevity
- Male
- Mutation
- Neurons
- Nuclear Proteins
- RNA-Binding Proteins
