Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sequence diversification and exon inactivation in the glycophorin A gene family from chimpanzee to human.

Journal of molecular evolution - 1 Oct 1995

Huang C H, Xie S S, Socha W, Blumenfeld O O

Abstract excerpt

In humans, the allelic diversity of MNSs glycophorins (GP) occurs mainly through the recombinational modulation of silent exons (pseudoexons) in duplicated genes. To address the origin of such a mechanism, structures of GPA, GPB, and GPE were determined in chimpanzee, the only higher primate known to have achieved a three-gene framework as in humans. Pairwise comparison of the chimpanzee and human genes revealed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Genetic Variation

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Share to Restriction Mapping

Source

Identifiers

PMID: 7563135
DOI: 10.1007/BF00160319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sequence diversification and exon inactivation in the glycophorin A gene family from chimpanzee to human.PMID 7563135Read ↗

Polymorphisms and gross structure of glycophorin genes in common chimpanzees.Semantic proximity Read ↗

Human pseudogenes of the ABO family show a complex evolutionary dynamics and loss of function.Semantic proximity Read ↗

Genetic differences between humans and great apes.Semantic proximity Read ↗

Structural and phylogenetic comparison of napsin genes: the duplication, loss of function and human-specific pseudogenization of napsin B.Semantic proximity Read ↗

Rapidly evolving genes in human. I. The glycophorins and their possible role in evading malaria parasites.Semantic proximity Read ↗

Evolution of the phosphoglycerate mutase processed gene in human and chimpanzee revealing the origin of a new primate gene.Semantic proximity Read ↗

A novel St(a) glycophorin produced via gene conversion of pseudoexon III from glycophorin E to glycophorin A gene.Semantic proximity Read ↗

A novel gene member of the human glycophorin A and B gene family. Molecular cloning and expression.Semantic proximity Read ↗

Gene conversion confined to a direct repeat of the acceptor splice site generates allelic diversity at human glycophorin (GYP) locus.Semantic proximity Read ↗

GBA3: a polymorphic pseudogene in humans that experienced repeated gene loss during mammalian evolutionSemantic proximity Read ↗

Sequence variability of a human pseudogene.Semantic proximity Read ↗

A mutation in human CMP-sialic acid hydroxylase occurred after the Homo-Pan divergence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.