Article
Molecular characterization and functional analysis of the major autolysin of Staphylococcus aureus 8325/4.
Journal of bacteriology - 1 Oct 1995
Foster S J
Abstract excerpt
The gene encoding the major autolysin of Staphylococcus aureus 8325/4 has been cloned, sequenced, and insertionally inactivated. The three-domain, 137,384-Da protein has a C-terminal glucosaminidase active site and is involved in cell separation, generalized cell lysis, and release of wall materi...
Topics
- Binding Sites
- Cell Wall
- Cloning, Molecular
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Hexosaminidases
- Molecular Sequence Data
- Mutation
- N-Acetylmuramoyl-L-alanine Amidase
- Recombinant Fusion Proteins
- Restriction Mapping
- Sequence Analysis, DNA
- Sodium Chloride
- Staphylococcus aureus
- Temperature