Article
Genetic test for pyruvate kinase deficiency of Basenjis.
Journal of the American Veterinary Medical Association - 1 Oct 1995
Whitney K M, Lothrop C D
Abstract excerpt
Pyruvate kinase (PK) deficiency is an autosomal, recessive, inherited disease of Basenjis that causes chronic, regenerative, hemolytic anemia. Diagnostic methods currently used to identify carrier animals rely on measurement of erythrocyte PK activity and frequently give equivocal results. A gene...
Topics
- Anemia, Hemolytic
- Animals
- Base Sequence
- Breeding
- DNA
- DNA Primers
- Dog Diseases
- Dogs
- Erythrocyte Count
- Erythrocytes
- Gene Deletion
- Genotype
- Hematocrit
- Molecular Sequence Data
- Osteosclerosis
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Primary Myelofibrosis