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Article

Erythrocytic pyruvate kinase mutations causing hemolytic anemia, osteosclerosis, and secondary hemochromatosis in dogs.

Journal of veterinary internal medicine - 1 Jan 2000

Gultekin G Inal, Raj K, Foureman P, Lehman S, Manhart K, Abdulmalik O, Giger U

Abstract excerpt

BACKGROUND: Erythrocytic pyruvate kinase (PK) deficiency, first documented in Basenjis, is the most common inherited erythroenzymopathy in dogs. OBJECTIVES: To report 3 new breed-specific PK-LR gene mutations and a retrospective survey of PK mutations in as mall and selected group of Beagles and West Highland White Terriers (WHWT). ANIMALS: Labrador Retrievers (2 siblings, 5 unrelated), Pugs (2 siblings, 1...

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Identifiers

PMID: 22805166
DOI: 10.1111/j.1939-1676.2012.00958.x
PMCID: PMC3650904

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