Statistical methodology for estimating twin similarity with respect to a dichotomous trait.

Abstract excerpt

Statistical methodology is presented for the estimation of twin similarity with respect to a dichotomous trait. The methodology focuses on the intraclass correlation as the parameter of interest and is analogous to methodology commonly applied to continuous outcome data. For inference problems involving a single sample, confidence interval construction and significance testing are discussed. For two sample...

Topics

• Confidence Intervals
• Humans
• Male
• Models, Genetic
• Models, Statistical
• Phenotype
• Probability
• Twins