Article
Validity of the zygosity questionnaire and characteristics of zygosity-misdiagnosed twin pairs in the Healthy Twin Study of Korea.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Jun 2010
Song Yun-Mi, Lee Donghun, Lee Mi Kyoung, Lee Kayoung, Lee Hee Jung, Hong Eun Jung, Han Bokghee, Sung Joohon
Abstract excerpt
Determining valid zygosity is a basic and important requirement in a twin study, because misdiagnosing zygosity leads to biased results. The Healthy Twin Study has collected data from adult like-sex twins and their families since 2005. In the study, a questionnaire to determine zygosity was developed comprising four questions; one concerning the degree of resemblance, and three concerning the degree of confusion...
Topics
- Adult
- Aged
- Aged, 80 and over
- Algorithms
- Decision Trees
- Female
- Genotype
- Humans
- Korea
- Male
- Middle Aged
- Predictive Value of Tests
- Sensitivity and Specificity