Article
Optimization of zygosity determination by questionnaire and DNA genotyping in Chinese adolescent twins.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Apr 2010
Chen Jie, Li Xinying, Chen Zhiyan, Yang Xiaodong, Zhang Jie, Duan Qing, Ge Xiaojia
Abstract excerpt
The main aim of this study was to develop and optimize a questionnaire-based zygosity determination method in Chinese adolescent twins. Participants were 471 pairs of same-sex twins (345 monozygotic, 126 dizygotic) with a mean age of 14.56 years (SD=2.62). A second sample was recruited for cross-validation, including 382 pairs of same-sex twins (261 monozygotic, 121 dizygotic) with a mean age of 12.53 years...
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