Article
RNAIII suppresses the expression of LtaS via acting as an antisense RNA in Staphylococcus aureus.
Journal of basic microbiology - 1 Feb 2015
Yan Jun, Liu Yu, Gao Yaping, Dong Jie, Mu Chunhua, Li Di, Yang Guang
Abstract excerpt
RNAIII is known as the key effector of staphylococcal accessory gene regulator (agr) quorum-sensing system, which plays a central role in the pathogenesis of Staphylococcus aureus. As a regulatory RNA, RNAIII regulates multiple targets, including exoproteins and cell-wall-associated proteins. Lipoteichoic acid synthase (LtaS) is involved in the synthesis of lipoteichoic acid (LTA) that is one of the major...
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