Article
Analysis of FGF function in normal and no tail zebrafish embryos reveals separate mechanisms for formation of the trunk and the tail.
Development (Cambridge, England) - 1 Sept 1995
Griffin K, Patient R, Holder N
Abstract excerpt
To analyse the roles of FGF activity and brachyury during gastrulation we have directly compared the consequences of inhibition of FGF-receptor signalling with the phenotype of the zebrafish brachyury mutant, no tail (ntl). We show that expression of ntl is regulated by FGF and that inhibition of...
Topics
- Animals
- DNA-Binding Proteins
- Fetal Proteins
- Fibroblast Growth Factors
- Gastrula
- Gene Expression Regulation, Developmental
- In Situ Hybridization
- Mesoderm
- Models, Genetic
- Morphogenesis
- Phenotype
- T-Box Domain Proteins
- Tail
- Zebrafish
- Brachyury Protein