Article
IGF-I and insulin receptors in bovine skeletal muscle: comparisons of different developmental ages, two different genotypes and various individual muscles.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association - 1 Jan 1995
Boge A, Sauerwein H, Meyer H H
Abstract excerpt
To investigate the regulation of the IGF-I and the insulin receptor in bovine skeletal muscle, we determined their concentrations and their affinity constants in animals of different age, muscle type and breed. Receptors were solubilized and measured by an enzyme-immunoassay. During ontogenesis the concentration of IGF-I receptors decreased from 1650 /+- 600 fmol/mg protein in 3-5-month old fetuses to 105 /+- 20...
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