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Article

Beta 1 integrins mediate adherent phenotype of human erythroblastic cell lines after phorbol 12-myristate 13-acetate induction.

The Biochemical journal - 15 Jul 1995

Molla A, Berthier R, Chapel A, Schweitzer A, Andrieux A

Abstract excerpt

We investigated the effects of phorbol ester (phorbol 12-myristate 13-acetate; PMA) treatment on the adhesive behaviour of three erythroleukaemia cell lines: HEL, LAMA-84 and AP217. In the three cell lines PMA induced an increase in expression of a megakaryocytic marker: alpha IIb beta 3 integrin, but did not promote activation of this receptor. Indeed, an antibody specific for the activated form of alpha IIb...

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Identifiers

PMID: 7542871
DOI: 10.1042/bj3090491
PMCID: PMC1135758

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Source receipt: pubmed, retrieved 7 Sept 2026.

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