Article
Lipopolysaccharide recovery restores susceptibility levels towards beta-lactams in Serratia marcescens.
Microbios - 1 Jan 1995
Palomar J, Puig M, Montilla R, Lorén J G, Viñas M
Abstract excerpt
O-side chain-defective spontaneous mutants of Serratia marcescens, selected by phage resistance, showed lower MICs against various beta-lactams than did their parental strains. The recovery of their ability to produce O-antigen restored the original MIC values, as well as phage susceptibility. Th...
Topics
- Anti-Bacterial Agents
- Cell Membrane Permeability
- Microbial Sensitivity Tests
- Mutation
- O Antigens
- Polysaccharides, Bacterial
- Serratia marcescens
- beta-Lactams