Article
Mutations in the sequence flanking the microsatellite at the KAP8 locus prevent the amplification of some alleles.
Animal genetics - 1 Feb 1995
Ede A J, Crawford A M
Abstract excerpt
The microsatellite described for the glycine- and tyrosine-rich keratin locus (KAP8) in sheep was used to type nine large three-generation families comprising the AgResearch International Mapping Flock. The apparent non-Mendelian inheritance in these families suggested that some of the microsatellite alleles were not being amplified. Sequence analysis showed that a deletion within one of the published primer...
Topics
- Alleles
- Animals
- Base Sequence
- Chromosome Mapping
- DNA, Satellite
- Female
- Gene Amplification
- Keratins
- Male
- Molecular Sequence Data
- Pedigree
- Sequence Deletion