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[Structural and functional relationships demonstrated by the study of V3 loop heterogeneity].

Revue roumaine de virologie (Bucharest, Romania : 1990) - 1 Jan 2000

Ruţă S

Abstract excerpt

Data obtained from genomic sequence analysis of the gp 120 V3 loop show that some of the phenotype features depend on the modifications produced in the amino acid sequence of this region. Phenotypical characterization of HIV isolates is based on their sensitivity to neutralizing antibodies, the appearance of virus variants showing unusual tropism, higher cytopathogenicity in vitro and modified virulence in vivo,...

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PMID: 7530033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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[Structural and functional relationships demonstrated by the study of V3 loop heterogeneity].PMID 7530033Read ↗

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A unique, naturally occurring single-amino acid mutation in HIV type 1 V3 loop can discriminate between its cytopathicity and replication in vivo and in vitro.Semantic proximity Read ↗

Sequence variation and consensus sequence of V3 loop on HIV-1 gp120.Semantic proximity Read ↗

Variability in the human immunodeficiency virus type 1 gp120 Env protein linked to phenotype-associated changes in the V3 loop.Semantic proximity Read ↗

HIV-1 gp120 V3 Loop for Structure-Based Drug DesignSemantic proximity Read ↗

Diversity of the V3 region of HIV in Paris, France.Semantic proximity Read ↗

V3 sequences of paired HIV-1 isolates from blood and cerebrospinal fluid cluster according to host and show variation related to the clinical stage of disease.Semantic proximity Read ↗

Small amino acid changes in the V3 hypervariable region of gp120 can affect the T-cell-line and macrophage tropism of human immunodeficiency virus type 1.Semantic proximity Read ↗

V3 loop of the human immunodeficiency virus type 1 Env protein: interpreting sequence variability.Semantic proximity Read ↗

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Mutations in the V3 stem versus the V3 crown and C4 region have different effects on the binding and fusion steps of human immunodeficiency virus type 1 gp120 interaction with the CCR5 coreceptorSemantic proximity Read ↗

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