Article
Management of pregnancy when maternal blood has a very high level of fetal haemoglobin.
British journal of haematology - 1 Oct 1994
Kaeda J S, Prasad K, Howard R J, Mehta A, Vulliamy T, Luzzatto L
Abstract excerpt
Fetal blood normally has a higher oxygen affinity than maternal blood because of the predominance of haemoglobin (Hb) F in the former and of Hb A in the latter; this predominance facilitates the transfer of oxygen from maternal to fetal blood. We report two patients who had exclusively or predominantly Hb F in their blood and were managed differently. When patient 1 became pregnant she had regular exchange blood...
Topics
- Adult
- Blood Transfusion
- Female
- Fetal Hemoglobin
- Genotype
- Globins
- Humans
- Mutation
- Oxygen
- Pregnancy
- Pregnancy Complications, Hematologic
- Pregnancy Outcome