Article
The HLA-B73 antigen has a most unusual structure that defines a second lineage of HLA-B alleles.
Tissue antigens - 1 May 1994
Parham P, Arnett K L, Adams E J, Barber L D, Domena J D, Stewart D, Hildebrand W H, Little A M
Abstract excerpt
The nucleotide sequence of cDNA encoding the HLA-B73 antigen was determined; it is unusually divergent, differing from other HLA-B alleles by 44-77 nucleotide substitutions. Features that distinguish the B*7301 heavy chain from other HLA-B heavy chains include multiple substitutions in the alpha 3 domain and a duplication-deletion within the transmembrane region that increases the length of B*7301 compared to...
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