Article
Association of pancreatic adenocarcinoma, mild lung disease, and delta F508 mutation in a cystic fibrosis patient.
Clinical chemistry - 1 Oct 1994
Tsongalis G J, Faber G, Dalldorf F G, Friedman K J, Silverman L M, Yankaskas J R
Abstract excerpt
A case of adenocarcinoma of the pancreas and mild lung disease in a 39-year-old man homozygous for the delta F508 cystic fibrosis mutation is presented. Cystic fibrosis is the most common lethal genetic disease in Caucasians, and is most commonly associated with severe obstructive lung disease. To our knowledge, this is only the fifth case of adenocarcinoma of the pancreas in a CF patient to be reported and the...
Topics
- Adenocarcinoma
- Adult
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Homozygote
- Humans
- Lung Diseases
- Male
- Membrane Proteins
- Mutagenesis, Site-Directed
- Mutation