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Article

Isochromosomes in neoplasia

1 Aug 1994

Abstract excerpt

In order to ascertain the frequency and distribution of isochromosomes in neoplasia, we surveyed the cytogenetic data from 20,007 tumors with clonal chromosome aberrations reported in the literature. Tumor types for which at least 50 cases with acquired aberrations and 10 cases with isochromosomes had been reported were selected, yielding a total of 18,160 neoplasms. Of these, 1,792 cases (9.9%) displayed a total...

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PMID: 7522535
DOI: 10.1002/gcc.2870100402

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