Article
Altered expression of ganglioside phenotypes of human gliomas in vivo and in vitro.
Molecular and chemical neuropathology - 1 Jan 2000
Wikstrand C J, Fredman P, McLendon R R, Svennerholm L, Bigner D D
Abstract excerpt
A library of epitope-defined antiganglioside monoclonal antibodies has been used to analyze the ganglioside phenotype of human glioma cell lines, rodent xenografts derived from them, and a separate panel of human glioma biopsies by multiple quantitative and qualitative assays. We have shown that...
Topics
- Animals
- Antibodies, Monoclonal
- Biopsy
- Carbohydrate Conformation
- Carbohydrate Sequence
- Cell Line
- Epitopes
- Gangliosides
- Glioma
- Humans
- Mice
- Mice, Nude
- Molecular Sequence Data
- Phenotype
- Transplantation, Heterologous
- Tumor Cells, Cultured
