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Article

Monoclonal antibodies to malignant human gliomas.

Molecular and chemical neuropathology - 1 Oct 1992

Wikstrand C J, Fredman P, Svennerholm L, Humphrey P A, Bigner S H, Bigner D D

Abstract excerpt

Operationally specific monoclonal antibodies (MAbs) reactive with tumor but not normal adult tissues offer great potential for diagnosis and therapy of CNS neoplasms. Two targets for specific MAb localization were chosen for this study: (1) glioma-associated gangliosides GM2 [II3NeuAc-GgOse3Cer], GD2 [II3(NeuAc)2-GgOse3Cer], GD3[II3(NeuAc)2-LacCer], 3'-isoLM1 [IV3NeuAc-LcOse4Cer], and 3',6'-isoLD1...

Topics

Adult
Antibodies, Monoclonal
Carbohydrate Sequence
Epitopes
ErbB Receptors
Gangliosides
Genetic Variation
Glioma
Humans
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1384525
DOI: 10.1007/BF03159988

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1384525-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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