Article
[PCR-based HCV genotyping with type-specific primers derived from core gene and IFN responsiveness].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jul 1994
Okamoto H
Abstract excerpt
Based on the sequence similarity of HCV isolates for which the entire nucleotide sequence is determined, at least five genotypes of HCV (I, II, III, IV and V) have been reported which differ from each other in more than 21% of approximately 9.4 kilobases. HCV genomes are classifiable into the five defined genotypes by PCR amplification with type-specific primers derived from core gene. Genotype of HCV appears to...
Topics
- Base Sequence
- Chronic Disease
- Genotype
- Hepacivirus
- Hepatitis C
- Humans
- Interferons
- Molecular Sequence Data
- Polymerase Chain Reaction
