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Article

Molecular characterization of the melanocyte lineage-specific antigen gp100.

1 Aug 1994

Abstract excerpt

The glycoproteins recognized by monoclonal antibody (mAb) NKI-beteb are among the best diagnostic markers for human melanoma because their expression is restricted to melanocytic cells. Recently, we isolated a cDNA clone, termed gp100-c1, which confers immunoreactivity not only to mAb NKI-beteb, but also to two other mAbs used to diagnose malignant melanoma, HMB-50 and HMB-45. In this report, we demonstrate that...

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PMID: 7519602
DOI: 10.1016/s0021-9258(17)32136-1

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