Article
Molecular basis of reduced or absent expression of decay-accelerating factor in Cromer blood group phenotypes.
Blood - 15 Aug 1994
Lublin D M, Mallinson G, Poole J, Reid M E, Thompson E S, Ferdman B R, Telen M J, Anstee D J, Tanner M J
Abstract excerpt
The human erythrocyte blood group system Cromer consists of high-incidence and low-incidence antigens that reside on decay-accelerating factor (DAF; CD55), a glycosyl-phosphatidylinositol-anchored membrane protein that regulates complement activation on cell surfaces. In the Cromer phenotypes Dr(a-) and Inab there is reduced or absent expression of DAF, respectively. This study investigated the molecular basis of...
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