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Article

Insertional activation of cepA leads to high-level beta-lactamase expression in Bacteroides fragilis clinical isolates

1 Jul 1994

Abstract excerpt

Bacteroides fragilis is an important opportunistic pathogen of humans and is resistant to many drugs commonly used to treat anaerobic infections, including beta-lactams. A strain set comprised of B. fragilis isolates producing either low or high levels of the endogenous cephalosporinase activity, CepA, has been described previously (M. B. Rogers, A. C. Parker, and C. J. Smith, Antimicrob. Agents Chemother....

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PMID: 7517394
DOI: 10.1128/jb.176.14.4376-4384.1994

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