Article
Alteration in lymphocyte phenotype associated with administration of adjuvant levamisole and 5-fluorouracil.
Cancer immunology, immunotherapy : CII - 1 Jun 1994
Holcombe R F, Stewart R M, Betzing K W, Kannan K
Abstract excerpt
Levamisole (LMS) and 5-fluorouracil (5FU) administered adjuvantly are effective in reducing the relapse rate following surgical resection of Duke's stage C colon carcinoma. It has been postulated that LMS acts to stimulate the immune system and that this is one mechanism through which this drug exerts its antitumor effects. In this study, peripheral blood mononuclear cells (PBMC) were analyzed in nine patients...
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