Article
Elemental microanalysis of fibroblasts by a scanning proton microprobe and application to Menkes' disease.
Biological trace element research - 1 Feb 1994
Allan G L, Camakaris J, Legge G J
Abstract excerpt
A scanning proton microprobe has been used for the elemental microanalysis of individual fibroblast cells. Both normal fibroblasts and fibroblasts cultured from patients with Menkes' disease, an X-linked genetic disorder known to be associated with defective copper metabolism, were examined by the probe. The cells were cultured on a thin ultra-clean nylon foil and retained on that surface for analysis. The...
Topics
- Cells, Cultured
- Chlorine
- Copper
- Electron Probe Microanalysis
- Fibroblasts
- Humans
- Iron
- Menkes Kinky Hair Syndrome
- Mutation
- Phosphorus
- Potassium
- Sulfur