Article
Phenotypic, genotypic, cytochemical, and ultrastructural characterization of acute undifferentiated leukemia.
Leukemia - 1 Sept 1990
Campana D, Hansen-Hagge T E, Matutes E, Coustan-Smith E, Yokota S, Shetty V, Bartram C R, Janossy G
Abstract excerpt
During the diagnostic investigation of 750 acute leukemias, nine cases were morphologically, cytochemically, and phenotypically undifferentiated. In seven of these cases the blasts were class II+, CD34+ and TdT+, in one were class II+, TdT+, CD7+ while in the remaining leukemia blasts expressed class II only. Cytoplasmic and membrane CD22, CD3, CD13, and Ig as well as membrane CD19, CD10, CD37, CD2, CD33, CD14,...
Topics
- Acute Disease
- Adolescent
- Aged
- Antigens, Differentiation
- Antineoplastic Combined Chemotherapy Protocols
- Enzyme Precursors
- Female
- Gene Rearrangement, B-Lymphocyte, Heavy Chain
- Gene Rearrangement, T-Lymphocyte
- Genotype