The fastest genome evolution ever described: HIV variation in situ.

doi:10.1016/0959-437x(93)90008-d

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Article

The fastest genome evolution ever described: HIV variation in situ.

Current opinion in genetics & development - 1 Dec 1993

Wain-Hobson S

Abstract excerpt

Human immunodeficiency virus is an RNA virus in which the degree of genetic variation observed is phenomenal--up to 20% within an infected individual. This is essentially due to remorseless cycles of viral replication, most probably due to chronic activation of the immune system. It can be estima...

Topics

Biological Evolution
Genetic Variation
Genome, Viral
HIV
HIV Infections
Humans
RNA-Directed DNA Polymerase
Time Factors

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