Article
Characterization of foot-and-mouth disease virus by monoclonal antibodies.
Viral immunology - 1 Jan 1993
Alonso A, Gomes M D, Ramalho A K, Allende R, Barahona H, Söndahl M S, Osorio F A
Abstract excerpt
Monoclonal antibodies (MAbs) were produced against foot-and-mouth disease (FMD) virus types O1 Campos Br1/58, A24 Cruzeiro Br1/55, and C3 Indaial Br1/71, which are the strains used for production of FMD vaccines in the majority of South American countries. Within the library of MAbs produced, a group was selected on the basis of their neutralizing titer in cell culture, protective titer in suckling mice,...
Topics
- Animals
- Antibodies, Monoclonal
- Aphthovirus
- Cattle
- Cells, Cultured
- Enzyme-Linked Immunosorbent Assay
- Epitopes
- Foot-and-Mouth Disease
- Mice
- Mice, Inbred BALB C
- Phenotype