Article
Antigenic analysis of Rift Valley fever virus isolates: monoclonal antibodies distinguish between wild-type and neurotropic virus strains.
Research in virology - 1 Jan 2000
Besselaar T G, Blackburn N K, Meenehan G M
Abstract excerpt
Rift Valley fever virus (RVFV) isolates from southern Africa were analysed for possible strain variation using monoclonal antibodies prepared against the South African prototype RVF 1830 strain. By the indirect immunofluorescence antibody assay and neutralization tests, the wild type southern African isolates were found to be antigenically similar to RVFV strains from other parts of Africa. In contrast,...
Topics
- Animals
- Antibodies, Monoclonal
- Antigens, Viral
- Fluorescent Antibody Technique
- Genetic Variation
- Humans
- Neurons
- Neutralization Tests
- Rift Valley Fever
- Rift Valley fever virus
- South Africa
