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[Blood screening for Down's syndrome in women under 35 years of age with an age-independent index].

Zeitschrift fur Geburtshilfe und Perinatologie - 1 Jan 2000

Benz R, Müller U, Krahner-Pilat M, Wagner-Geuder S, Terinde R

Abstract excerpt

The need for alternatives to amniocentesis, beset by 1% abortion rate, has been increasingly voiced over the past years and also includes the under 35 age group. However, the known age-dependent screening programs such as Alpha program according to Wald (1988) and the Dermalog Program according to Norgaard-Pederson (1990) only yield a detection rate of 50 or, at best, 70% (Müller, 1992) for this age group. We...

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PMID: 7505992

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