Article
The appropriate upper age limit for semen donors: a review of the genetic effects of paternal age.
Fertility and sterility - 1 Sept 1991
Bordson B L, Leonardo V S
Abstract excerpt
There is little evidence to support a correlation between increased paternal age and the incidence of chromosome anomalies. Though a few early studies demonstrated an increased risk of Down syndrome with advanced paternal age, especially after the age of 55, numerous later studies failed to confirm any paternal age effect. Among structural chromosome anomalies, only the inherited reciprocal translocations were...
Topics
- Chromosome Aberrations
- Chromosome Disorders
- Gene Rearrangement
- Humans
- Insemination, Artificial, Heterologous
- Male
- Mutation
- Paternal Age
- Semen