Article
The ribosomal DNA loci in Plasmodium falciparum accumulate mutations independently.
Journal of molecular biology - 15 Dec 1995
Rogers M J, McConkey G A, Li J, McCutchan T F
Abstract excerpt
Homogeneity of rDNA sequence within a cell is maintained by mechanisms working at the DNA level. The imperative to maintain homogeneity is thought to result from pressure to maintain the sequence of the rRNA transcript. We have investigated the extent of sequence variation within and between members of a species that is unable to utilize some standard mechanisms of rDNA sequence correction. We have compared the...
Topics
- Animals
- Base Sequence
- DNA, Ribosomal
- Genes, Protozoan
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Plasmodium falciparum
- Sequence Alignment
- Sequence Analysis
