Article
Functional equivalence of structurally distinct ribosomes in the malaria parasite, Plasmodium berghei.
The Journal of biological chemistry - 22 Jun 2001
van Spaendonk R M, Ramesar J, van Wigcheren A, Eling W, Beetsma A L, van Gemert G J, Hooghof J, Janse C J, Waters A P
Abstract excerpt
Unlike most eukaryotes, many apicomplexan parasites contain only a few unlinked copies of ribosomal RNA (rRNA) genes. Based on stage-specific expression of these genes and structural differences among the rRNA molecules it has been suggested that Plasmodium spp. produce functionally different ribosomes in different developmental stages. This hypothesis was investigated through comparison of the structure of the...
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