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Article

Identification of functional domains of the aryl hydrocarbon receptor.

The Journal of biological chemistry - 8 Dec 1995

Fukunaga B N, Probst M R, Reisz-Porszasz S, Hankinson O

Abstract excerpt

Functional domains of the mouse aryl hydrocarbon receptor (Ahr) were investigated by deletion analysis. Ligand binding was localized to a region encompassing the PAS B repeat. The ligand-mediated dissociation of Ahr from the 90-kDa heat shock protein (HSP90) does not require the aryl hydrocarbon receptor nuclear translocator (Arnt), but it is slightly enhanced by this protein. One HSP90 molecule appears to bind...

Topics

Animals
Aryl Hydrocarbon Receptor Nuclear Translocator
DNA-Binding Proteins
HSP90 Heat-Shock Proteins
Helix-Loop-Helix Motifs
Mice
Mutation
Polychlorinated Dibenzodioxins
Receptors, Aryl Hydrocarbon
Transcription Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Cells, Cultured

Source

Identifiers

PMID: 7493958
DOI: 10.1074/jbc.270.49.29270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7493958-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Identification of functional domains of the aryl hydrocarbon receptor.PMID 7493958Read ↗

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