Article
Identification of functional domains of the aryl hydrocarbon receptor.
The Journal of biological chemistry - 8 Dec 1995
Fukunaga B N, Probst M R, Reisz-Porszasz S, Hankinson O
Abstract excerpt
Functional domains of the mouse aryl hydrocarbon receptor (Ahr) were investigated by deletion analysis. Ligand binding was localized to a region encompassing the PAS B repeat. The ligand-mediated dissociation of Ahr from the 90-kDa heat shock protein (HSP90) does not require the aryl hydrocarbon receptor nuclear translocator (Arnt), but it is slightly enhanced by this protein. One HSP90 molecule appears to bind...
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